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Effect of phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 on the function of reversing factor in the initiation of protein synthesis.

The reticulocyte reversing factor (RF) isolated as a complex with eukaryotic initiation factor 2 (eIF-2) acts catalytically in restoring protein synthesis in reticulocyte lysates inhibited by heme deficiency. In reconstituted in vitro assay mixtures containing Mg2+ (0.25-0.5 mM), RF catalyzes the fo...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Matts, R L, Levin, D H, London, I M
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1983
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6573671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.9.2559
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