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Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2

Incubation of reticulocyte lysates or isolated crude ribosomes with low levels of double-stranded RNA (0.1-10 ng/ml) induces the formation of an inhibitor of protein synthesis initiation similar to that observed in heme deficiency. The inhibitor is associated with a cyclic AMP-independent protein ki...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Levin, Daniel, London, Irving M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/274704/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.3.1121
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