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Hepatic Carboxylesterase 1 Is Essential for Both Normal and Farnesoid X Receptor-Controlled Lipid Homeostasis
Non-alcoholic fatty liver disease (NAFLD) is one of the major health concerns worldwide. Farnesoid X receptor (FXR) is considered a therapeutic target for treatment of NAFLD. However, the mechanism by which activation of FXR lowers hepatic triglyceride (TG) levels remains unknown. Here we investigat...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938573/ https://ncbi.nlm.nih.gov/pubmed/24038130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26714 |
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