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Binding and inhibition of drug transport proteins by heparin: A potential drug transporter modulator capable of reducing multidrug resistance in human cancer cells

A major problem in cancer treatment is the development of resistance to chemotherapeutic agents, multidrug resistance (MDR), associated with increased activity of transmembrane drug transporter proteins which impair cytotoxic treatment by rapidly removing the drugs from the targeted cells. Previousl...

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Detalhes bibliográficos
Main Authors: Chen, Yunliang, Scully, Michael, Petralia, Gloria, Kakkar, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938516/
https://ncbi.nlm.nih.gov/pubmed/24253450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27148
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