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Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology
Analog-sensitive (AS) kinase technology is a powerful approach for studying phospho-signaling pathways in diverse organisms and physiological processes. The key feature of this technique is that a kinase-of-interest can be mutated to sensitize it to inhibitor analogs that do not target wild-type (WT...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938282/ https://ncbi.nlm.nih.gov/pubmed/24171479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408704u |
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