Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia

In a randomized controlled blinded trial, 2-year-old purpose-bred beagles (n = 24), with Staphylococcus aureus pneumonia, were exchanged-transfused with either 7- or 42-day-old washed or unwashed canine universal donor blood (80 mL/kg in 4 divided doses). Washing red cells (RBC) before transfusion h...

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Detalhes bibliográficos
Main Authors: Cortés-Puch, Irene, Wang, Dong, Sun, Junfeng, Solomon, Steven B., Remy, Kenneth E., Fernandez, Melinda, Feng, Jing, Kanias, Tamir, Bellavia, Landon, Sinchar, Derek, Perlegas, Andreas, Solomon, Michael A., Kelley, Walter E., Popovsky, Mark A., Gladwin, Mark T., Kim-Shapiro, Daniel B., Klein, Harvey G., Natanson, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938151/
https://ncbi.nlm.nih.gov/pubmed/24366359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-539353
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