CD8(+)T cell–specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8(+)T cell accumulation in tumors

BACKGROUND: Increased infiltration of CD8(+)T cells into tumors has a positive impact on survival. Our previous study showed that doxorubicin (Dox) plus interleukin-12 (IL-12) boosted the accumulation of CD8(+)T cells in tumors and had a greater antitumor effect than did either agent alone. The purp...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hu, Jiemiao, Zhu, Shiguo, Xia, Xueqing, Zhang, Liangfang, Kleinerman, Eugenie S, Li, Shulin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938086/
https://ncbi.nlm.nih.gov/pubmed/24565056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-34
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky