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CD8(+)T cell–specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8(+)T cell accumulation in tumors
BACKGROUND: Increased infiltration of CD8(+)T cells into tumors has a positive impact on survival. Our previous study showed that doxorubicin (Dox) plus interleukin-12 (IL-12) boosted the accumulation of CD8(+)T cells in tumors and had a greater antitumor effect than did either agent alone. The purp...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938086/ https://ncbi.nlm.nih.gov/pubmed/24565056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-34 |
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