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Regulation of NKG2D(+)CD8(+) T-cell-mediated antitumor immune surveillance: Identification of a novel CD28 activation-mediated, STAT3 phosphorylation-dependent mechanism

The natural killer (NK) group 2D (NKG2D) receptor, which displays on mouse and human NK cells, activates CD8(+) T cells and small subsets of other T cells. NKG2D(+)CD8(+) T cells play critical roles in both innate and adaptive immunity upon engagement with NKG2D ligands to eliminate tumor and infect...

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Détails bibliographiques
Publié dans:Oncoimmunology
Auteurs principaux: Hu, Jiemiao, Batth, Izhar S., Xia, Xueqing, Li, Shulin
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214668/
https://ncbi.nlm.nih.gov/pubmed/28123894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1252012
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