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Functions of NKG2D in CD8(+) T cells: an opportunity for immunotherapy

Natural killer group 2 member D (NKG2D) is a type II transmembrane receptor. NKG2D is present on NK cells in both mice and humans, whereas it is constitutively expressed on CD8(+) T cells in humans but only expressed upon T-cell activation in mice. NKG2D is a promiscuous receptor that recognizes str...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Prajapati, Kushal, Perez, Cynthia, Rojas, Lourdes Beatriz Plaza, Burke, Brianna, Guevara-Patino, Jose A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068164/
https://ncbi.nlm.nih.gov/pubmed/29400704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.161
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