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ESE-1 Is a Potent Repressor of Type II Collagen Gene (COL2A1) Transcription In Human Chondrocytes

The epithelium-specific ETS (ESE)-1 transcription factor is induced in chondrocytes by interleukin-1β (IL-1β). We reported previously that early activation of EGR-1 by IL-1β results in suppression of the proximal COL2A1 promoter activity by displacement of Sp1 from GC boxes. Here we report that ESE-...

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Bibliographische Detailangaben
Hauptverfasser: PENG, HAIBING, TAN, LUJIAN, OSAKI, MAKOTO, ZHAN, YUMEI, IJIRI, KOSEI, TSUCHIMOCHI, KANEYUKI, OTERO, MIGUEL, WANG, HONG, CHOY, BOB K., GRALL, FRANCK T., GU, XUESONG, LIBERMANN, TOWIA A., OETTGEN, PETER, GOLDRING, MARY B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937869/
https://ncbi.nlm.nih.gov/pubmed/18044710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21338
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