Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice

Growth arrest and DNA damage-inducible protein 45 β (GADD45β) is expressed in normal and early osteoarthritic articular cartilage. We recently reported that GADD45β enhances CCAAT/enhancer binding protein β (C/EBPβ) activation in vitro. This study was undertaken in order to determine whether GADD45β...

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Detalhes bibliográficos
Main Authors: Shimada, Hirofumi, Sakakima, Harutoshi, Tsuchimochi, Kaneyuki, Matsuda, Fumiyo, Komiya, Setsuro, Goldring, Mary B., Ijiri, Kosei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427738/
https://ncbi.nlm.nih.gov/pubmed/21353395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2011.01.007
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