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Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological changes (increase healthspan). Yet, a comprehensive comparison of the metabolic phenotype across different genetic backgrounds to identify comm...

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Main Authors: Collino, Sebastiano, Martin, François-Pierre J., Montoliu, Ivan, Barger, Jamie L., Da Silva, Laeticia, Prolla, Tomas A., Weindruch, Richard, Kochhar, Sunil
格式: Artigo
語言:Inglês
出版: MDPI 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937836/
https://ncbi.nlm.nih.gov/pubmed/24958256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo3040881
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