Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological changes (increase healthspan). Yet, a comprehensive comparison of the metabolic phenotype across different genetic backgrounds to identify comm...

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Autori principali: Collino, Sebastiano, Martin, François-Pierre J., Montoliu, Ivan, Barger, Jamie L., Da Silva, Laeticia, Prolla, Tomas A., Weindruch, Richard, Kochhar, Sunil
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937836/
https://ncbi.nlm.nih.gov/pubmed/24958256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo3040881
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