Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival

ATP8A2 is a P(4)-ATPase that is highly expressed in the retina, brain, spinal cord and testes. In the retina, ATP8A2 is localized in photoreceptors where it uses ATP to transport phosphatidylserine (PS) and phosphatidylethanolamine (PE) from the exoplasmic to the cytoplasmic leaflet of membranes. Al...

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Detalles Bibliográficos
Main Authors: Coleman, Jonathan A., Zhu, Xianjun, Djajadi, Hidayat R., Molday, Laurie L., Smith, Richard S., Libby, Richard T., John, Simon W. M., Molday, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937779/
https://ncbi.nlm.nih.gov/pubmed/24413176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.145052
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