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Calcineurin-NFATc Regulates Type 2 Inositol 1,4,5-Trisphosphate Receptor (InsP(3)R2) Expression during Cardiac Remodeling
In heart, the type 2 inositol 1,4,5-triphosphate receptor (InsP(3)R2) is the predominant isoform expressed and is localized in the nuclear membrane of ventricular myocytes. InsP(3)R2-mediated Ca(2+) release regulates hypertrophy specific gene expression by modulating CaMKIIδ, histone deacetylase, an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937684/ https://ncbi.nlm.nih.gov/pubmed/24415751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.495242 |
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