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Histone Deacetylase Inhibitors Modulate Interleukin 6-dependent CD4(+) T Cell Polarization in Vitro and in Vivo

Histone deacetylase (HDAC) inhibitors have been associated primarily with an anti-proliferative effect in vitro and in vivo. Recent data provide evidence for an anti-inflammatory potency of HDAC inhibitors in models of experimental colitis. Because the balance of T cell subpopulations is critical fo...

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Bibliografske podrobnosti
Main Authors: Glauben, Rainer, Sonnenberg, Elena, Wetzel, Martin, Mascagni, Paolo, Siegmund, Britta
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937680/
https://ncbi.nlm.nih.gov/pubmed/24421314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.517599
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