Receptor-interacting Protein 1 Increases Chemoresistance by Maintaining Inhibitor of Apoptosis Protein Levels and Reducing Reactive Oxygen Species through a microRNA-146a-mediated Catalase Pathway

Although receptor-interacting protein 1 (RIP1) is well known as a key mediator in cell survival and death signaling, whether RIP1 directly contributes to chemotherapy response in cancer has not been determined. In this report, we found that, in human lung cancer cells, knockdown of RIP1 substantiall...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Qiong, Chen, Wenshu, Bai, Lang, Chen, Wenjie, Padilla, Mabel T., Lin, Amy S., Shi, Shaoqing, Wang, Xia, Lin, Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937640/
https://ncbi.nlm.nih.gov/pubmed/24425875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526152
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