Receptor-interacting Protein 1 Increases Chemoresistance by Maintaining Inhibitor of Apoptosis Protein Levels and Reducing Reactive Oxygen Species through a microRNA-146a-mediated Catalase Pathway

Although receptor-interacting protein 1 (RIP1) is well known as a key mediator in cell survival and death signaling, whether RIP1 directly contributes to chemotherapy response in cancer has not been determined. In this report, we found that, in human lung cancer cells, knockdown of RIP1 substantiall...

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Detalhes bibliográficos
Main Authors: Wang, Qiong, Chen, Wenshu, Bai, Lang, Chen, Wenjie, Padilla, Mabel T., Lin, Amy S., Shi, Shaoqing, Wang, Xia, Lin, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937640/
https://ncbi.nlm.nih.gov/pubmed/24425875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526152
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