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Inherent Asymmetry in the 26S Proteasome Is Defined by the Ubiquitin Receptor RPN13*

The 26S double-capped proteasome is assembled in a hierarchic event that is orchestrated by dedicated set of chaperons. To date, all stoichiometric subunits are considered to be present in equal ratios, thus providing symmetry to the double-capped complex. Here, we show that although the vast majori...

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Autores principales: Berko, Dikla, Herkon, Ora, Braunstein, Ilana, Isakov, Elada, David, Yael, Ziv, Tamar, Navon, Ami, Stanhill, Ariel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937637/
https://ncbi.nlm.nih.gov/pubmed/24429290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509380
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