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Assessment of Myeloperoxidase Activity by the Conversion of Hydroethidine to 2-Chloroethidium
Oxidants derived from myeloperoxidase (MPO) contribute to inflammatory diseases. In vivo MPO activity is commonly assessed by the accumulation of 3-chlorotyrosine (3-Cl-Tyr), although 3-Cl-Tyr is formed at low yield and is subject to metabolism. Here we show that MPO activity can be assessed using h...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937635/ https://ncbi.nlm.nih.gov/pubmed/24436331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539486 |
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