Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

Sterol regulatory element-binding protein-1 (SREBP-1) is a key transcription factor that regulates genes in the de novo lipogenesis and glycolysis pathways. The levels of SREBP-1 are significantly elevated in obese patients and in animal models of obesity and type 2 diabetes, and a vast number of st...

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Detalhes bibliográficos
Main Authors: Ruiz, Rafaela, Jideonwo, Victoria, Ahn, Miwon, Surendran, Sneha, Tagliabracci, Vincent S., Hou, Yongyong, Gamble, Aisha, Kerner, Janos, Irimia-Dominguez, José M., Puchowicz, Michelle A., DePaoli-Roach, Anna, Hoppel, Charles, Roach, Peter, Morral, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937627/
https://ncbi.nlm.nih.gov/pubmed/24398675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541110
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