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Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice
Disruption of the Gys2 gene encoding the liver isoform of glycogen synthase generates a mouse strain (LGSKO) that almost completely lacks hepatic glycogen, has impaired glucose disposal, and is pre-disposed to entering the fasted state. This study investigated how the lack of liver glycogen increase...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481557/ https://ncbi.nlm.nih.gov/pubmed/28483921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786525 |
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