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The Chiral Potential of Phenanthriplatin and Its Influence on Guanine Binding

[Image: see text] The monofunctional platinum complex cis-[Pt(NH(3))(2)Cl(Am)](+), also known as phenanthriplatin, where Am is the N-heterocyclic base phenanthridine, has promising anticancer activity. Unlike bifunctional compounds such as cisplatin, phenanthriplatin can form only one covalent bond...

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Bibliografiske detaljer
Main Authors: Johnstone, Timothy C., Lippard, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937553/
https://ncbi.nlm.nih.gov/pubmed/24417436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4125115
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