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Cells injected with guanosine 5'-[alpha, beta-methylene]triphosphate, an alpha, beta-nonhydrolyzable analog of GTP, show anomalous patterns of tubulin polymerization affecting cell translocation, intracellular movement, and the organization of Golgi elements.

Injection of the alpha, beta-nonhydrolyzable GTP analog, guanosine 5'-[alpha, beta-methylene]triphosphate (pp[CH2]pG) into PtK2, A549, and Swiss 3T3 cells produced dramatic changes in the normal pattern of long radiating microtubules displayed by the cells before injection. Injection of pp[CH2]...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Wehland, J, Sandoval, I V
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1983
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6572952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.7.1938
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