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Hydroxyl radical oxidation of guanosine 5′-triphosphate (GTP): requirement for a GTP-Cu(II) complex
Levels of oxidized guanosine (G) base in DNA have become a hallmark biomarker in assessing oxidative stress implicated in a variety of disease and toxin-induced states. However, there is evidence that the G in the nucleotide triphosphate pool (GTP) is more susceptible to oxidation than Gs incorporat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759603/ https://ncbi.nlm.nih.gov/pubmed/19389276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/135100009X392520 |
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