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Hydroxyl radical oxidation of guanosine 5′-triphosphate (GTP): requirement for a GTP-Cu(II) complex

Levels of oxidized guanosine (G) base in DNA have become a hallmark biomarker in assessing oxidative stress implicated in a variety of disease and toxin-induced states. However, there is evidence that the G in the nucleotide triphosphate pool (GTP) is more susceptible to oxidation than Gs incorporat...

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Detaylı Bibliyografya
Asıl Yazarlar: Cerchiaro, Giselle, Bolin, Celeste, Cardozo-Pelaez, Fernando
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759603/
https://ncbi.nlm.nih.gov/pubmed/19389276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/135100009X392520
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