Mammalian E-type Cyclins Control Chromosome Pairing, Telomere Stability and CDK2 Localization in Male Meiosis

Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type cyclins during spermatogenesis, we characterized their expression patterns and produced additional deletions of C...

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Main Authors: Martinerie, Laetitia, Manterola, Marcia, Chung, Sanny S. W., Panigrahi, Sunil K., Weisbach, Melissa, Vasileva, Ana, Geng, Yan, Sicinski, Peter, Wolgemuth, Debra J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937215/
https://ncbi.nlm.nih.gov/pubmed/24586195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004165
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