Mammalian E-type Cyclins Control Chromosome Pairing, Telomere Stability and CDK2 Localization in Male Meiosis

Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type cyclins during spermatogenesis, we characterized their expression patterns and produced additional deletions of C...

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Detalhes bibliográficos
Main Authors: Martinerie, Laetitia, Manterola, Marcia, Chung, Sanny S. W., Panigrahi, Sunil K., Weisbach, Melissa, Vasileva, Ana, Geng, Yan, Sicinski, Peter, Wolgemuth, Debra J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937215/
https://ncbi.nlm.nih.gov/pubmed/24586195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004165
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