Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.

Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type cyclins during spermatogenesis, we characterized their expression patterns and produced additional deletions of C...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Laetitia Martinerie, Marcia Manterola, Sanny S W Chung, Sunil K Panigrahi, Melissa Weisbach, Ana Vasileva, Yan Geng, Peter Sicinski, Debra J Wolgemuth
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2014-02-01
Серии:PLoS Genetics
Online-ссылка:http://europepmc.org/articles/PMC3937215?pdf=render
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы