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Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B
Cisplatin, carboplatin, and oxaliplatin are widely used anticancer drugs. Their efficacy is strongly reduced by development of cell resistance, a phenomenon not entirely understood, with contribution of drug detoxification, defective accumulation, and efflux from the cell. Down-regulation of CTR1, r...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937162/ https://ncbi.nlm.nih.gov/pubmed/24375922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307718 |
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