Distinctive Features of Catalytic and Transport Mechanisms in Mammalian Sarco-endoplasmic Reticulum Ca(2+) ATPase (SERCA) and Cu(+) (ATP7A/B) ATPases

Ca(2+) (sarco-endoplasmic reticulum Ca(2+) ATPase (SERCA)) and Cu(+) (ATP7A/B) ATPases utilize ATP through formation of a phosphoenzyme intermediate (E-P) whereby phosphorylation potential affects affinity and orientation of bound cation. SERCA E-P formation is rate-limited by enzyme activation by C...

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Main Authors: Lewis, David, Pilankatta, Rajendra, Inesi, Giuseppe, Bartolommei, Gianluca, Moncelli, Maria Rosa, Tadini-Buoninsegni, Francesco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463298/
https://ncbi.nlm.nih.gov/pubmed/22854969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373472
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