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The Interdomain Long-Range Electron Transfer Becomes Rate-Limiting in the Y216A Variant of Tyramine β-Monooxygenase()

The enzyme, tyramine β-monoxygenase (TβM), belongs to a small eukaryotic family of physiologically important mononuclear dicopper monooxygenases. The properties of this family include non-coupled mononuclear copper centers ca. 11 Å apart, with the Cu(M) performing C–H and O(2) activation and Cu(H) f...

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Autors principals: Osborne, Robert L., Zhu, Hui, Iavarone, Anthony T., Blackburn, Ninian J., Kilnman, Judith P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936603/
https://ncbi.nlm.nih.gov/pubmed/23320946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3013609
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