CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban

Increasing heart rate enhances cardiac contractility (force frequency relationship, FFR) and accelerates cardiac relaxation (frequency-dependent acceleration of relaxation, FDAR). The positive FFR together with FDAR promotes rapid filling and ejection of blood from the left ventricle (LV) at higher...

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Bibliografiske detaljer
Main Authors: Wu, Yiming, Luczak, Elizabeth D, Lee, Eun-Jeong, Hidalgo, Carlos, Yang, Jinying, Gao, Zhan, Li, Jingdong, Wehrens, Xander, Granzier, Henk, Anderson, Mark E
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936404/
https://ncbi.nlm.nih.gov/pubmed/22796260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.06.019
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