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Antibody-targeted liposomes: increase in specific toxicity of methotrexate-gamma-aspartate.

Liposomes conjugated with anti-H2Kk antibody associate with L929 murine fibroblasts in 6- to 20-fold greater amount than do nonspecific liposomes. The ability of methotrexate-gamma-aspartate to inhibit L929 growth is increased 10-fold when encapsulated in targeted liposomes but is decreased to 50% w...

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Bibliografische gegevens
Hoofdauteurs: Heath, T D, Montgomery, J A, Piper, J R, Papahadjopoulos, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC393600/
https://ncbi.nlm.nih.gov/pubmed/6572395
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