Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

Epidermal growth factor (EGF) at 3 nM maximally inhibits the proliferation of A431 epidermoid carcinoma cells. We show that at lower concentrations, in the range of 3-100 pM, EGF has a mitogenic effect on A431 cells. In the presence of 100 nM anti-EGF-receptor monoclonal IgG (designated 528), which...

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Detalhes bibliográficos
Main Authors: Kawamoto, T, Sato, J D, Le, A, Polikoff, J, Sato, G H, Mendelsohn, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC393592/
https://ncbi.nlm.nih.gov/pubmed/6298788
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