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SOCS3 Inhibits Antiviral IFN-β Signaling to Enhance HIV-1 Replication in Macrophages()

HIV-1 replication within macrophages of the CNS often results in cognitive and motor impairment, which is known as HIV-associated dementia (HAD) in its most severe form. IFN-β suppresses viral replication within these cells during early CNS infection, but the effect is transient. HIV-1 eventually ov...

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Main Authors: Akhtar, Lisa Nowoslawski, Qin, Hongwei, Muldowney, Michelle T., Yanagisawa, Lora L., Kutsch, Olaf, Clements, Janice E., Benveniste, Etty N.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935802/
https://ncbi.nlm.nih.gov/pubmed/20631305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903563
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