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SOCS3 Inhibits Antiviral IFN-β Signaling to Enhance HIV-1 Replication in Macrophages()
HIV-1 replication within macrophages of the CNS often results in cognitive and motor impairment, which is known as HIV-associated dementia (HAD) in its most severe form. IFN-β suppresses viral replication within these cells during early CNS infection, but the effect is transient. HIV-1 eventually ov...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935802/ https://ncbi.nlm.nih.gov/pubmed/20631305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903563 |
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