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TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice
Although autoantibodies are the hallmarks of most autoimmune diseases, the mechanisms by which autoreactive B cells are generated and accumulate are still poorly understood. Overexpression of Toll-like receptor 7 (TLR7) that recognizes single-stranded RNAs has been implicated in systemic lupus eryth...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935605/ https://ncbi.nlm.nih.gov/pubmed/22945807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-012-8365-8 |
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