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Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergy

BACKGROUND: Monoclonal antibodies directed at IgE demonstrate clinical efficacy in subjects with peanut allergy, but previous studies have not addressed the kinetics of the clinical response or the role of mast cells and basophils in the food-induced allergic response. OBJECTIVE: We sought to determ...

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Autors principals: Savage, Jessica H., Courneya, Jean-Paul, Sterba, Patricia M., MacGlashan, Donald W., Saini, Sarbjit S., Wood, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935509/
https://ncbi.nlm.nih.gov/pubmed/22800401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.05.039
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