Effects of Omalizumab on Basophil and Mast Cell Responses using an Intranasal Cat Allergen Challenge

BACKGROUND: Omalizumab treatment suppresses FcεRI expression faster on blood basophils than skin mast cells. OBJECTIVE: We utilized omalizumab to elucidate the relative contributions of basophil versus mast cell FcεRI activation in a nasal allergen challenge (NAC) model. METHODS: Eighteen cat-allerg...

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Huvudupphovsmän: Eckman, John A., Sterba, Patricia M., Kelly, Denise, Alexander, Val, Liu, Mark C., Bochner, Bruce S., MacGlashan, Donald W., Saini, Sarbjit S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850969/
https://ncbi.nlm.nih.gov/pubmed/19962744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.09.012
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