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Structure, sarcomeric organization and thin filament binding of cardiac myosin binding protein-C

Myosin-binding protein C (MyBP-C) is an accessory protein of the myosin filaments of vertebrate striated muscle. In the heart it plays a key role in modulating contractility in response to β-adrenergic stimulation. Mutations in the cardiac isoform (cMyBP-C) are a leading cause of inherited hypertrop...

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Bibliographic Details
Main Authors: Craig, Roger, Lee, Kyoung Hwan, Mun, Ji Young, Torre, Iratxe, Luther, Pradeep K.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935486/
https://ncbi.nlm.nih.gov/pubmed/24413886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-013-1426-6
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