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In vitro discrimination of replicases acting on carcinogen-modified polynucleotide templates

Three different poly(dC)s with modifications that block the N-3 of deoxycytidine were used as templates for polymer synthesis by Escherichia coli DNA polymerase I (EC 2.7.7.7). In contrast to previously reported results with transcriptases, the hydrated form of 3,N(4)-ethenodeoxycytidine (εdC·H(2)O)...

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Main Authors: Singer, B., Kuśmierek, J. T., Fraenkel-Conrat, H.
格式: Artigo
語言:Inglês
出版: 1983
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC393509/
https://ncbi.nlm.nih.gov/pubmed/6573665
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