The effect of antibiotics on the T4 polynucleotide ligase catalyzed template dependent polymerization of oligodeoxythymidylates.

The poly(dA) dependent T4 polynucleotide ligase catalyzed polymerization of oligodeoxythymidylates is dependent upon duplex stability. The antibiotics ethidium bromide, netropsin and Hoechst 33258 stabilize the duplex poly(dA) . P(dT)n (n = 6-10) to thermal denaturation. Ethidium bromide to DNA rati...

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Main Authors: Kalisch, B W, van de Sande, J H
格式: Artigo
語言:Inglês
出版: 1979
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC327818/
https://ncbi.nlm.nih.gov/pubmed/450717
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