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Enhanced MGMT expression contributes to temozolomide resistance in glioma stem-like cells
O(6)-methylguanine DNA methyltransferase (MGMT) can remove DNA alkylation adducts, thereby repairing damaged DNA and contributing to the drug resistance of gliomas to alkylating agents. In addition, glioma stem-like cells (GSCs) have been demonstrated to be involved in the recurrence and treatment r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Sun Yat-sen University Cancer Center
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935013/ https://ncbi.nlm.nih.gov/pubmed/23958055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10236 |
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