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Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters

A series of des-keto lobeline analogs has been synthesized and evaluated for their ability to inhibit the dopamine transporter (DAT) and serotonin transporter (SERT) function and for their affinity for the synaptic vesicle monoamine transporter (VMAT2), as well as for α4β2(*) and α7(*) neuronal nico...

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Main Authors: Zheng, Guangrong, Horton, David B., Deaciuc, Agripina G., Dwoskin, Linda P., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934794/
https://ncbi.nlm.nih.gov/pubmed/16905316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.07.070
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