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ABCA1 in adipocytes regulates adipose tissue lipid content, glucose tolerance, and insulin sensitivity

Adipose tissue contains one of the largest reservoirs of cholesterol in the body. Adipocyte dysfunction in obesity is associated with intracellular cholesterol accumulation, and alterations in cholesterol homeostasis have been shown to alter glucose metabolism in cultured adipocytes. ABCA1 plays a m...

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Bibliografiske detaljer
Main Authors: de Haan, Willeke, Bhattacharjee, Alpana, Ruddle, Piers, Kang, Martin H., Hayden, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934735/
https://ncbi.nlm.nih.gov/pubmed/24443560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M045294
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