High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation

Obesity-induced liver inflammation can drive insulin resistance. HDL has anti-inflammatory properties, so we hypothesized that low levels of HDL would perpetuate inflammatory responses in the liver and that HDL treatment would suppress liver inflammation and insulin resistance. The aim of this study...

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Detalhes bibliográficos
Main Authors: McGrath, Kristine C., Li, Xiao Hong, Whitworth, Phillippa T., Kasz, Robert, Tan, Joanne T., McLennan, Susan V., Celermajer, David S., Barter, Philip J., Rye, Kerry-Anne, Heather, Alison K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934727/
https://ncbi.nlm.nih.gov/pubmed/24347528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M043281
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