High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation

Obesity-induced liver inflammation can drive insulin resistance. HDL has anti-inflammatory properties, so we hypothesized that low levels of HDL would perpetuate inflammatory responses in the liver and that HDL treatment would suppress liver inflammation and insulin resistance. The aim of this study...

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Bibliografiske detaljer
Main Authors: McGrath, Kristine C., Li, Xiao Hong, Whitworth, Phillippa T., Kasz, Robert, Tan, Joanne T., McLennan, Susan V., Celermajer, David S., Barter, Philip J., Rye, Kerry-Anne, Heather, Alison K.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934727/
https://ncbi.nlm.nih.gov/pubmed/24347528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M043281
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