High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation

Obesity-induced liver inflammation can drive insulin resistance. HDL has anti-inflammatory properties, so we hypothesized that low levels of HDL would perpetuate inflammatory responses in the liver and that HDL treatment would suppress liver inflammation and insulin resistance. The aim of this study...

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Autori principali: McGrath, Kristine C., Li, Xiao Hong, Whitworth, Phillippa T., Kasz, Robert, Tan, Joanne T., McLennan, Susan V., Celermajer, David S., Barter, Philip J., Rye, Kerry-Anne, Heather, Alison K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934727/
https://ncbi.nlm.nih.gov/pubmed/24347528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M043281
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