Quantitative correlation of homogeneously stained regions on chromosome 10 with dihydrofolate reductase enzyme in human cells.

Gene amplification may be visualized within a chromosome as a homogeneously stained region (HSR) and HSRs have rarely been reported in human tumor cells with identification of the amplified gene. A parental line and seven clones derived from KB cells resistant to methotrexate (MTX) contain dihydrofo...

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Hlavní autoři: Wolman, S R, Craven, M L, Grill, S P, Domin, B A, Cheng, Y C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1983
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC393469/
https://ncbi.nlm.nih.gov/pubmed/6572370
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