Correlation of unstable multidrug cross resistance in Chinese hamster ovary cells with a homogeneously staining region on chromosome 1.

An enrichment selection method using repeated pulses of low drug concentration (1 microgram/ml) was used to isolate CHO (AK412) variants that are 20-fold more resistant to cytochalasin D (CD). CD-resistant (CydR) variants possess a unique unstable phenotype, including a longer doubling time in nonse...

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Bibliografiske detaljer
Main Authors: Grund, S H, Patil, S R, Shah, H O, Pauw, P G, Stadler, J K
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370017/
https://ncbi.nlm.nih.gov/pubmed/6633534
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