Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.

Methotrexate-resistant Chinese hamster ovary cells selected for high resistance by progressive increments of methotrexate in the culture medium have levels of dihydrofolate reductase (tetrahydrofolate dehydrogenase, 7,8-dihydrofolate: NADP+ oxidoreductase, EC 1.5.1.3) 200 times that of sensitive cel...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nunberg, J H, Kaufman, R J, Schimke, R T, Urlaub, G, Chasin, L A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1978
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC393004/
https://ncbi.nlm.nih.gov/pubmed/281704
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky